Investigations into the metabolic fate and distribution of hepzidine maleate in the rat and the mouse.

@article{Hespe1968InvestigationsIT,
  title={Investigations into the metabolic fate and distribution of hepzidine maleate in the rat and the mouse.},
  author={W. Hespe and H Prins and W. F. Kafoe and W. Th. Nauta},
  journal={Biochemical pharmacology},
  year={1968},
  volume={17 5},
  pages={
          655-66
        }
}
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11 Citations

11 Citations

Aspects of the biliary excretion of orphenadrine and its N-demethylated derivative, tofenacin, in the rat.
Distribution of tritium-labelled tofenacine hydrochloride in the pregnant mouse.
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Absorption, Distribution, Metabolism, and Elimination of Antihistamines
TLDR
Readers of this chapter are cautioned to evaluate carefully the significance and interpretation of metabolic studies which do not make use of radiolabeled drugs.
Distribution of hexamethonium and other quaternary ammonium compounds in cartilage.
  • K. Asghar, L. J. Roth
  • Biology, Medicine
    The Journal of pharmacology and experimental therapeutics
  • 1971
TLDR
It is hypothesized that the diquaternary ammonium compounds, under physiologic conditions, are bound to the polyanionic mucopolysaccharide components of cartilaginous tissue, including those of intervertebral discs.
Chapter 23. Drug Metabolism
Structure-activity relationships in drug-induced pancreatic islet cell toxicity.
Etherspaltung, ein metabolischer Nebenweg des Etofenamatabbaus bei Versuchstieren
Neben den Hauptabbauwegen des Etofenamats bei Versuchstieren und Menschen (Hydroxylierung, Esterspaltung und Konjugation) wurde in der Etherspaltung ein metabolischer Nebenweg gefunden. Nach…
Pharmaceutical sciences--1970: literature review of pharmaceutics.
This review of the literature represents a comprehensive cross section of the research and development efforts in various selected disciplines of the pharmaceutical sciences. It is the ninth annual…
Diphenhydramine Derivatives: Through Manipulation toward Design
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