Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

Abstract

SET-M33 is a multimeric antimicrobial peptide active against Gram-negative bacteria in vitro and in vivo. Insights into its killing mechanism could elucidate correlations with selectivity. SET-M33 showed concentration-dependent bactericidal activity against colistin-susceptible and resistant isolates of P. aeruginosa and K. pneumoniae. Scanning and… (More)
DOI: 10.1016/j.bbamem.2017.06.001

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Cite this paper

@article{Weide2017InvestigationsIT, title={Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.}, author={Hessel van der Weide and Jlenia Brunetti and Alessandro Pini and Luisa Bracci and Chiara Ambrosini and Pietro Lupetti and Eugenio Paccagnini and Mariangela Gentile and Andrea Bernini and Neri Niccolai and Denise Vermeulen-de Jongh and Irma A. J. M. Bakker-Woudenberg and Wil H. F. Goessens and John P. Hays and Chiara Falciani}, journal={Biochimica et biophysica acta}, year={2017}, volume={1859 10}, pages={1796-1804} }