Investigational treatment options in microscopic colitis

@article{Madisch2008InvestigationalTO,
  title={Investigational treatment options in microscopic colitis},
  author={Ahmed Madisch and Andrea Morgner and Manfred Stolte and Stephan Miehlke},
  journal={Expert Opinion on Investigational Drugs},
  year={2008},
  volume={17},
  pages={1829 - 1837}
}
Collagenous and lymphocytic colitis are the two recognized major presentations of microscopic colitis. Both diseases present with chronic watery diarrhea and a chronic inflammatory infiltrate in the colonic mucosa without specific endoscopic abnormalities, and hence diagnosis is established by histology. Recent epidemiological studies suggest that microscopic colitis may affect as many patients as Crohn's disease or ulcerative colitis. The cause of these diseases is unknown; however, several… 
1 Citations
Microscopic Colitis: Epidemiology, Pathophysiology, Diagnosis and Current Management—An Update 2013
  • M. Storr
  • Medicine
    ISRN gastroenterology
  • 2013
TLDR
The present knowledge of the epidemiology, the pathophysiology, and the diagnosis of microscopic colitis is summarized and the former and the present treatment options are discussed.

References

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TLDR
Nine patients with chronic watery diarrhea and nonspecific colonic mucosal inflammation followed for 1-5 yr are presented, and histological variability of collagenization and inflammation during the course of collagenous colitis and microscopic Colitis and the clinical feature of watery diarrhoea suggest that these two entities be grouped together as theWatery diarrhea-colitis syndrome.
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TLDR
Empirical data demonstrates that microscopic colitis is a more common cause of diarrhea than previously shown, and studies on treatment have demonstrated budesonide to be most effective, although other treatments also hold promise.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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