Investigational drugs for coagulation disorders.

@article{Mannucci2013InvestigationalDF,
  title={Investigational drugs for coagulation disorders.},
  author={Pier Mannuccio Mannucci and Maria Elisa Mancuso},
  journal={Expert opinion on investigational drugs},
  year={2013},
  volume={22 8},
  pages={
          945-53
        }
}
INTRODUCTION The current standard treatment in persons with hemophilia (PWH) is prophylaxis, given intravenously twice or thrice weekly, which is associated with a non negligible burden on patients' quality of life. Therefore the main attempts aiming to improve the management of PWH are targeted towards the development of a new generation of coagulation factors endowed with properties facilitating prophylaxis and/or a better control of bleeding. AREAS COVERED This article summarizes the main… CONTINUE READING
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