Investigational anabolic therapies for osteoporosis.

  title={Investigational anabolic therapies for osteoporosis.},
  author={Ritu Trivedi and Ravinder Goswami and Naibedya Chattopadhyay},
  journal={Expert opinion on investigational drugs},
  volume={19 8},
IMPORTANCE OF THE FIELD Anabolic therapy, or stimulating the function of bone-forming osteoblasts, is the preferred pharmacological intervention for osteoporosis. AREAS COVERED IN THIS REVIEW We reviewed bone anabolic agents currently under active investigation. The bone anabolic potential of IGF-I and parathyroid hormone-related protein is discussed in the light of animal data and human studies. We also discuss the use of antagonists of the calcium-sensing receptor (calcilytics) as orally… CONTINUE READING