Investigation on the stability of saquinavir loaded liposomes: implication on stealth, release characteristics and cytotoxicity.

Although anti-retroviral therapy is the most efficient disease management strategy for HIV-AIDS, its applications are limited by several factors including the low bioavailability and first pass metabolism of the drugs. Nanocarriers such as liposomes have been developed to circumvent some of these problems. We report here preparation of novel liposome… (More)