Investigation of the type of induction of microsomal monooxygenases by polycyclic hydrocarbons.

@article{Tsyrlov1979InvestigationOT,
  title={Investigation of the type of induction of microsomal monooxygenases by polycyclic hydrocarbons.},
  author={I. B. Tsyrlov and N B Rivkind and Vyacheslav V. Lyakhovich},
  journal={Biology bulletin of the Academy of Sciences of the USSR},
  year={1979},
  volume={6 1},
  pages={28-34}
}
The severity of the induced effect of the polycyclic hydrocarbon 3-methylcholanthrene on monooxygenase of the microsomal fraction of the liver as a function of the number of binding sites for this inducer in the active site of cytochrome P-450 was investigated. In vivo models, in which the primary bounding and metabolism of a polycyclic hydrocarbon in the… CONTINUE READING