Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches.

Abstract

As a classical formula, Sini decoction (SND) has been fully proved to be clinically effective in treating doxorubicin (DOX)-induced cardiomyopathy. Current chemomics and pharmacology proved that the total alkaloids (TA), total gingerols (TG), total flavones and total saponins (TFS) are the major active ingredients of Aconitum carmichaelii, Zingiber… (More)
DOI: 10.1039/c4mb00048j

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@article{Chen2014InvestigationOT, title={Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches.}, author={Si Chen and Si Wu and Wuhong Li and Xiaofei Chen and Xin Dong and Guangguo Tan and Hai Zhang and Zhanying Hong and ZhenYu Zhu and Yifeng Chai}, journal={Molecular bioSystems}, year={2014}, volume={10 12}, pages={3310-21} }