Investigation of the subtype of alpha 2-adrenoceptor mediating pressor responses in the pithed rat.

@article{Gavin1996InvestigationOT,
  title={Investigation of the subtype of alpha 2-adrenoceptor mediating pressor responses in the pithed rat.},
  author={Kenneth Gavin and James Docherty},
  journal={European journal of pharmacology},
  year={1996},
  volume={318 1},
  pages={81-7}
}
We have investigated the subtype of alpha 2-adrenoceptor mediating postjunctional pressor responses in the pithed rat in comparison with alpha 2-adrenoceptor ligand binding sites. In pithed rats, postjunctional alpha 2-adrenoceptors were investigated in terms of the ability of alpha 2-adrenoceptor antagonists to shift the pressor potency of the alpha 2-adrenoceptor agonist xylazine. Antagonist potency at postjunctional alpha 2-adrenoceptors in the pithed rat was correlated with antagonist… CONTINUE READING