Investigation of the state and dynamics of water in hydrogels of cellulose ethers by1H NMR spectroscopy

@article{Baumgartner2002InvestigationOT,
  title={Investigation of the state and dynamics of water in hydrogels of cellulose ethers by1H NMR spectroscopy},
  author={Sa{\vs}a Baumgartner and Gojmir Lahajnar and Ana Sepe and Julijana Kristl},
  journal={AAPS PharmSciTech},
  year={2002},
  volume={3},
  pages={86-93}
}
The aim of this work was to study the effect of the type of substituent of the cellulose ethers and the molecular mass on the state and dynamics of water in the respective hydrogels to specify the quantity of adsorbed water on the polymers or, more explicitly, to calculate the average number of water molecules bound to a polymer repeating unit (PRU).1H NMR relaxation experiments were performed on equilibrated systems of cellulose ether polymers (HEC, HPC, HPMC K4M, and HPMC K100M) with water… CONTINUE READING
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