Investigation of the phase transitions occurring during and after the dehydration of xylazine hydrochloride monohydrate.

This paper reports an investigation of a complex solid state phase transition where two inter-converting polymorphs (X and A) of the pharmaceutical molecule xylazine hydrochloride formed and transformed during and after the dehydration of its monohydrate (H). The crystal structures of all three forms were compared. During the investigation of this solid… CONTINUE READING