Investigation of the opioid system in absence seizures with positron emission tomography.

Abstract

The neuroanatomical and pathophysiological basis of primary generalised absences is uncertain. Administration of endogenous opioids has been shown to result in absence-like seizures in animal models. Positron emission tomography scans were performed in eight patients with primary generalised epilepsy and eight control subjects. Regional cerebral blood flow… (More)

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@article{Bartenstein1993InvestigationOT, title={Investigation of the opioid system in absence seizures with positron emission tomography.}, author={Peter Bartenstein and John S. Duncan and Martin Prevett and Vincent J. Cunningham and Daniel R Fish and A. K. Jones and Soumya Luthra and Guy V Sawle and Denise Brooks}, journal={Journal of neurology, neurosurgery, and psychiatry}, year={1993}, volume={56 12}, pages={1295-302} }