Investigation of the metal binding site in methionine aminopeptidase by density functional theory

Abstract

All methionine aminopeptidases exhibit the same conserved metal binding site. The structure of this site with either Co2+ ions or Zn2+ ions was investigated using density functional theory. The calculations showed that the structure of the site was not influenced by the identity of the metal ions. This was the case for both of the systems studied; one based… (More)
DOI: 10.1023/A:1020119527789

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