Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems.


The modified ISCOMs, so-called Posintro nanoparticles, provide an opportunity for altering the surface charge of the particles, which influences their affinity for the negatively charged antigen sites, cell membranes and lipids in the skin. Hypothetically, this increases the passage of the ISCOMs (or their components) and their load through the stratum… (More)
DOI: 10.1016/j.bbamem.2010.06.006