Investigation of the effects of hesperidin and chrysin on renal injury induced by colistin in rats.

@article{Hanedan2018InvestigationOT,
  title={Investigation of the effects of hesperidin and chrysin on renal injury induced by colistin in rats.},
  author={B. Hanedan and M. Ozkaraca and A. Kırbaş and F. Kandemir and M. Aktaş and K. Kilic and S. Çomaklı and Sefa Kucukler and A. Bilgili},
  journal={Biomedicine \& pharmacotherapy = Biomedecine \& pharmacotherapie},
  year={2018},
  volume={108},
  pages={
          1607-1616
        }
}
This study aimed to investigate whether hesperidin and chrysin antioxidants have protective effects on renal injury induced by colistin in rats. Renal lipid peroxidation, total glutathione (GSH) levels, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) enzyme activities, serum urea and creatinine levels, as well as tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) levels were determined. Injuries to the proximal and distal tubules… Expand
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