Investigation of the effect of various shellac coating compositions containing different water-soluble polymers on in vitro drug release.

@article{Qussi2005InvestigationOT,
  title={Investigation of the effect of various shellac coating compositions containing different water-soluble polymers on in vitro drug release.},
  author={Basel Qussi and Wolfgang G Suess},
  journal={Drug development and industrial pharmacy},
  year={2005},
  volume={31 1},
  pages={99-108}
}
In this study drug pellets were coated with aqueous shellac coating formulations containing different amounts of polyvinyl alcohol (PVA), hydroxypropyl methylcellulose (HPMC), and carbomer 940. The coating level needed for enteric coating was determined. The influence of different amounts of PVA, HPMC, and carbomer on drug release and mechanism; the porosity, and the stability of shellac coatings was investigated. The results show that the incorporation of different concentrations of HPMC into… CONTINUE READING