Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.

  title={Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.},
  author={Mark F. Mohamed and A. A. Neverov and R. Brown},
  journal={Inorganic chemistry},
  volume={48 23},
Two sets of dinuclear Zn(II) complexes were prepared to determine the effect of the presence of oxyanionic bridging groups between the metal centers on the catalytic activity toward the methanolysis of the RNA analogue 2-hydroxypropyl-4-nitrophenyl phosphate (HPNPP, 2). The Zn(II)2 complexes of bis(di-(2-pyridylmethyl)amino)-m-xylene (6) and 2,6-bis(di-(2-pyridylmethyl)amino)-4-methylphenol (7) were compared to assess the effect of a bridging phenoxide ligand, while the Zn(II)2 complex of 1,3… Expand
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