Investigation of the antimicrobial activity of a short cationic peptide against promastigote and amastigote forms of Leishmania major (MHRO/IR/75/ER): An in vitro study.

@article{Khalili2018InvestigationOT,
  title={Investigation of the antimicrobial activity of a short cationic peptide against promastigote and amastigote forms of Leishmania major (MHRO/IR/75/ER): An in vitro study.},
  author={Sara Khalili and Elahe Ebrahimzade and Mehdi Mohebali and Parviz Shayan and Samira Mohammadi-Yeganeh and Mehrdad Moosazadeh Moghaddam and Samira Elikaee and Behnaz Akhoundi and Mohammad Kazem Sharifi-Yazdi},
  journal={Experimental parasitology},
  year={2018},
  volume={196},
  pages={
          48-54
        }
}
Cutaneous leishmaniasis is one of the most endemic global health problems in many countries all around the world. Pentavalent antimonial drugs constitute the first line of leishmaniasis treatment; however, resistance to these drugs is a serious problem. Therefore, new therapies with new modes of action are urgently needed. In the current study, we examined antimicrobial activity of CM11 hybrid peptide (WKLFKKILKVL-NH2) against promastigote and amastigote forms of L. major (MHRO/IR/75/ER). In… CONTINUE READING
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