Corpus ID: 28749219

Investigation of the anti-inflammatory, antinociceptive effect of ellagic acid as measured by digital paw pressure via the Randall-Selitto meter in male Sprague-Dawley rats.

@article{Gainok2011InvestigationOT,
  title={Investigation of the anti-inflammatory, antinociceptive effect of ellagic acid as measured by digital paw pressure via the Randall-Selitto meter in male Sprague-Dawley rats.},
  author={Jeffrey Gainok and R. Daniels and David Golembiowski and Patricia Kindred and Lisa Post and R. Strickland and N. Garrett},
  journal={AANA journal},
  year={2011},
  volume={79 4 Suppl},
  pages={
          S28-34
        }
}

Jeffrey Gainok, R. Daniels, +4 authors N. Garrett

Published 2011

Chemistry, Medicine

AANA journal

Ellagic acid (EA), a dietary supplement, is purported to have anti-inflammatory, antinociceptive properties via cyclooxygenase (COX) inhibition. We measured the antinociceptive efficacy of EA alone and in combination with a nonselective COX inhibitor and a selective COX-2 inhibitor. We assigned 54 male Sprague-Dawley rats to 1 of 6 groups to be given the following compounds: (1) vehicle, (2) ketorolac (nonselective COX inhibitor), (3) meloxicam (selective COX-2 inhibitor), (4) EA, (5) EA plus… CONTINUE READING

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