Investigation of the anti-inflammatory, antinociceptive effect of ellagic acid as measured by digital paw pressure via the Randall-Selitto meter in male Sprague-Dawley rats.
@article{Gainok2011InvestigationOT, title={Investigation of the anti-inflammatory, antinociceptive effect of ellagic acid as measured by digital paw pressure via the Randall-Selitto meter in male Sprague-Dawley rats.}, author={Jeffrey Gainok and R. Daniels and David Golembiowski and Patricia Kindred and Lisa Post and R. Strickland and N. Garrett}, journal={AANA journal}, year={2011}, volume={79 4 Suppl}, pages={ S28-34 } }
Ellagic acid (EA), a dietary supplement, is purported to have anti-inflammatory, antinociceptive properties via cyclooxygenase (COX) inhibition. We measured the antinociceptive efficacy of EA alone and in combination with a nonselective COX inhibitor and a selective COX-2 inhibitor. We assigned 54 male Sprague-Dawley rats to 1 of 6 groups to be given the following compounds: (1) vehicle, (2) ketorolac (nonselective COX inhibitor), (3) meloxicam (selective COX-2 inhibitor), (4) EA, (5) EA plus… CONTINUE READING
28 Citations
Ellagic acid enhances the antinociceptive action of venlafaxine in mouse acetic acid-induced pain: An isobolographic analysis.
- Chemistry, Medicine
- Pharmacological reports : PR
- 2015
- 11
Ellagic acid enhances the antinociceptive action of carbamazepine in the acetic acid writhing test with mice
- Chemistry, Medicine
- Pharmaceutical biology
- 2016
- 8
Antinociceptive and anti-inflammatory activities of a pomegranate (Punica granatum L.) extract rich in ellagitannins
- Medicine
- International journal of food sciences and nutrition
- 2015
- 27
Anti-hyperalgesic effects of AG490, a Janus kinase inhibitor, in a rat model of inflammatory pain.
- Medicine
- Biomedical reports
- 2015
- 10
- PDF
Ellagic acid enhances morphine analgesia and attenuates the development of morphine tolerance and dependence in mice.
- Chemistry, Medicine
- European journal of pharmacology
- 2014
- 23
Anti-inflammatory and antinociceptive activities of the leaf methanol extract of Miconia minutiflora (Bonpl.) DC. and characterization of compounds by UPLC-DAD-QTOF-MS/MS
- Chemistry, Medicine
- Naunyn-Schmiedeberg's Archives of Pharmacology
- 2018
- 5
Comparative Study of Anti-nociceptive Activity and Phenolic Content of the Ethanol Extracts of Piper nigrum and Piper longum Fruits
- Chemistry
- 2014
- 10
- PDF
In Vivo Anti-Inflammatory and in Vitro Antioxidant Activities of Toona Ciliata Leaves Native to Bangladesh
- Biology
- 2015
- 1
- PDF
The polyphenol ellagic acid exerts anti-inflammatory actions via disruption of store-operated calcium entry (SOCE) pathway activators and coupling mediators.
- Chemistry, Medicine
- European journal of pharmacology
- 2020
References
SHOWING 1-10 OF 35 REFERENCES
Evaluation of the anti-inflammatory effects of ellagic acid.
- Medicine
- Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
- 2010
- 61
Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.
- Medicine
- The Journal of pharmacology and experimental therapeutics
- 1992
- 642
Pharmacological profile of parecoxib: a novel, potent injectable selective cyclooxygenase-2 inhibitor.
- Medicine
- European journal of pharmacology
- 2004
- 73
Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production.
- Medicine
- The Journal of pharmacology and experimental therapeutics
- 1997
- 227
Involvement of peripheral prostaglandins in formalin-induced nociceptive behaviours in the orofacial area of rats
- Medicine
- InflammoPharmacology
- 2006
- 16
Antinociceptive activity of alcoholic extract of Hemidesmus indicus R.Br. in mice.
- Medicine
- Journal of ethnopharmacology
- 2005
- 104
The thrombopenic effect of ellagic acid in the rat. Another model of platelet stimulation "in vivo".
- Chemistry, Medicine
- Thrombosis research
- 1987
- 14
Comparison of Ketorolac Tromethamine with Other Injectable Nonsteroidal Anti-Inflammatory Drugs for Pain-on-Injection and Muscle Damage in the Rat
- Medicine
- Human & experimental toxicology
- 1994
- 17
Anti‐inflammatory, analgesic and anti‐oedematous effects of Lafoensia pacari extract and ellagic acid
- Chemistry, Medicine
- The Journal of pharmacy and pharmacology
- 2006
- 72
Distribution and metabolism of ellagic acid in the mouse following intraperitoneal administration.
- Chemistry, Medicine
- Cancer letters
- 1987
- 21