Investigation of the Stabilizing Effects of Antioxidants and Benzophenone-3 on Desonide Photostability

@article{Rosa2014InvestigationOT,
  title={Investigation of the Stabilizing Effects of Antioxidants and Benzophenone-3 on Desonide Photostability},
  author={Priscila Vieira Rosa and Ana Paula Snovarski Salla and Cristiane de Bona da Silva and Clarice Madalena Bueno Rolim and Andr{\'e}a In{\^e}s Horn Adams},
  journal={AAPS PharmSciTech},
  year={2014},
  volume={15},
  pages={1155-1162}
}
Desonide is a topical corticoid used in the treatment of skin diseases and is marketed in different pharmaceutical dosage forms. Recently, the poor photostability of a commercially available hair solution after direct exposure to UVA light was verified. In this study, we investigated the ability of the antioxidants ascorbic acid, butylhydroxyanisole (BHA), butylhydroxytoluene (BHT), α-tocopherol, and the UV filter benzophenone-3 (BP-3) to prevent the photodegradation of desonide in hair… Expand
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