Investigation of the Drug Release and Surface Morphological Properties of Film-Coated Pellets, and Physical, Thermal and Mechanical Properties of Free Films as a Function of Various Curing Conditions

@article{Bhattacharjya2008InvestigationOT,
  title={Investigation of the Drug Release and Surface Morphological Properties of Film-Coated Pellets, and Physical, Thermal and Mechanical Properties of Free Films as a Function of Various Curing Conditions},
  author={Sushmita Bhattacharjya and Dale Eric Wurster},
  journal={AAPS PharmSciTech},
  year={2008},
  volume={9},
  pages={449-457}
}
The purpose of the present investigation was to elucidate the influence of curing on different physical properties of Eudragit® NE and RS coating systems. Increased curing times resulted in decreased drug release rates from Eudragit® NE-coated beads. However, an increase in drug release rates was noticed at longer curing times and higher temperatures for the Eudragit® RS coating system. The surface morphological changes of the film-coated beads revealed that there were no visible macroscopic… CONTINUE READING

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