Investigation of the Curvature Induction and Membrane Localization of the In fl uenza Virus M 2 Protein Using Static and O ff-Magic-Angle Spinning Solid-State Nuclear Magnetic Resonance of Oriented

A wide variety of membrane proteins induce membrane curvature for function; thus, it is important to develop new methods to simultaneously determine membrane curvature and protein binding sites in membranes with multiple curvatures. We introduce solid-state nuclear magnetic resonance (NMR) methods based on magnetically oriented bicelles and off-magic-angle… (More)