Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA

@article{Hasler2009InvestigationOS,
  title={Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA},
  author={Felix Hasler and Erich Studerus and Kerstin Lindner and Stephan Ludewig and F. X. Vollenweider},
  journal={Journal of Psychopharmacology},
  year={2009},
  volume={23},
  pages={923 - 935}
}
Serotonin (5-HT) release is the primary pharmacological mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) action in the primate brain. Dopamine release and direct stimulation of dopamine D2 and serotonin 5-HT2A receptors also contributes to the overall action of MDMA. The role of 5-HT1A receptors in the human psychopharmacology of MDMA, however, has not yet been elucidated. In order to reveal the consequences of manipulation at the 5-HT1A receptor system on cognitive and… 
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