Investigation of respiratory disease in IBR vaccinated dairy herds

@article{Penny2013InvestigationOR,
  title={Investigation of respiratory disease in IBR vaccinated dairy herds},
  author={Colin D. Penny},
  journal={Veterinary Record},
  year={2013},
  volume={172},
  pages={109 - 110}
}
  • C. Penny
  • Published 25 January 2013
  • Medicine
  • Veterinary Record
AS part of its pharmacovigilance obligations, Pfizer Animal Health has been involved in a number of investigations over the past six months involving suspected lack of efficacy to both live attenuated and inactivated infectious bovine rhinotracheitis (IBR) vaccines. In all cases, the investigations have been triggered by reports of cows showing signs of respiratory disease suspected to be IBR and a higher than expected incidence of cows culled due to chronic pneumonia, despite on-label… 
4 Citations
An outbreak of infectious bovine rhinotracheitis (IBR) in a herd vaccinated with a live glycoprotein E deleted (marker) bovine herpesvirus 1 (BoHV-1) vaccine: lessons to be learned
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The virus and the diseases it causes are described, and options for diagnosis, vaccination, control and eradication are discussed, and possible priorities for further study are discussed.
The Incidence, Clinical, Haematological and Biochemical Measurement of Blood Parameters of Infectious Bovine Rhinotracheitis (IBR) in Cattle Bredding by the Public in Uşak Region
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Sonuc olarak, IBR enfeksiyonunun hematolojik ve biyokimyasal parametrelerle birlikte degerlendirilmesinin hayvan sagligi ile pratikte ilgilenen veterinerler icin oldukca faydali olacagi goruldu.
Bovine herpesvirus 1 infection in cattle: a discussion on vaccination and control
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A range of approaches have been taken to vaccination to protect against this disease, including gene-deleted marker vaccines that have facilitated a differentiation of infection from vaccination (DIVA) approach to diagnosis and herd health.

References

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Dynamics of bovine herpesvirus type 1 infection in Estonian dairy herds with and without a control programme
TLDR
To detect the efficacy of vaccination programmes in lowering the seroprevalence of BHV-1 gE within the dairy herd and to follow the dynamics of the infection in non-vaccinated herds with uninfected heifers, a two-year longitudinal study was carried out.
Assessment of the long-term effect of vaccination on transmission of infectious bovine rhinotracheitis virus in cattle herds hyperimmunized with glycoprotein E-deleted marker vaccine.
TLDR
Hyperimmunization via repeated administration of attenuated and inactivated-virus gE-deleted marker vaccines as well as inactivated -virus vaccines may provide a method for control of IBR.