Investigation of protein oxidation and lipid peroxidation in patients with rheumatoid arthritis.

@article{Bakol2006InvestigationOP,
  title={Investigation of protein oxidation and lipid peroxidation in patients with rheumatoid arthritis.},
  author={G{\"u}lden Başkol and Huseyin Seckin Demir and Mevlut Başkol and Eser Kilic and Filiz Bakar Ateş and Cigdem Karakukcu and Muzaffer Ustdal},
  journal={Cell biochemistry and function},
  year={2006},
  volume={24 4},
  pages={
          307-11
        }
}
We aimed to determine the importance of neutrophil activation and the source of oxidative stress in the pathogenesis of rheumatoid arthritis (RA) by quantification of advanced oxidation protein products (AOPP) and total thiol levels as markers of oxidative protein damage, malondialdehyde (MDA) levels as a marker of lipid peroxidation and myeloperoxidase (MPO) activity as a marker of neutrophil activation in patients with RA. Fifty-seven rheumatoid arthritis patients were included in the study… CONTINUE READING
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