Investigation of porcine natural-killer cell activity with reference to African swine-fever virus infection.

@article{Norley1983InvestigationOP,
  title={Investigation of porcine natural-killer cell activity with reference to African swine-fever virus infection.},
  author={Stephen G. Norley and Richard C. Wardley},
  journal={Immunology},
  year={1983},
  volume={49 4},
  pages={593-7}
}
The natural killing of the human myeloid leukaemia cell line by pig mononuclear cells was investigated in an 18 hr assay; the most active natural-killer (NK) effectors were those cells not adhering to nylon-wool columns or rosetting with sheep red blood cells. Mononuclear cells cultured in the presence of African swine-fever virus maintained NK activity. Pigs infected with African swine-fever virus exhibited a suppressed NK activity, possibly due to the sensitivity of NK cells to increased… CONTINUE READING