Investigation of neurokinin-2 and -3 receptors in the human and pig bladder.

Abstract

OBJECTIVE To investigate the role of neurokinin (NK)-2 and -3 receptors in mediating the contraction of detrusor muscle strips from human and pig, to determine whether the pig is a good model for the study of tachykinin receptors in the human bladder, as the biological actions of tachykinins, e.g. substance P and NKA are mediated via three distinct receptor… (More)

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