Investigation of nano-mechanical properties of annulus fibrosus using atomic force microscopy.

@article{Lewis2008InvestigationON,
  title={Investigation of nano-mechanical properties of annulus fibrosus using atomic force microscopy.},
  author={Naama T. L. Lewis and Mohammad Asif Hussain and Jeremy J Mao},
  journal={Micron},
  year={2008},
  volume={39 7},
  pages={
          1008-19
        }
}
We describe the use of atomic force microscopy (AFM) to investigate the nanomechanical properties of annulus fibrosus (AF)-the outer fibrous layer of an intervertebral disc (IVD) encapsulating the inner jelly-like mass known as the nucleus pulposus (NP). Disk disease, degenerated discs, slipped discs, and herniated discs are common terms often linked to back pain and are caused due to degeneration of IVD. Due to the variations in the structure and biochemical composition of the IVD, studies of… CONTINUE READING
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