Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms.

@article{Ramage2002InvestigationOM,
  title={Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms.},
  author={Gordon Ramage and Stefano P Bachmann and Thomas F. Patterson and Brian L. Wickes and Jose L Lopez-Ribot},
  journal={The Journal of antimicrobial chemotherapy},
  year={2002},
  volume={49 6},
  pages={
          973-80
        }
}
A main characteristic associated with microbial biofilms is their increased resistance to antimicrobial chemotherapies. However, at present very little is known about the phenotypic changes that occur during the transition from the planktonic to the biofilm mode of growth. Candida albicans biofilms displayed an organized three-dimensional structure, and consisted of a dense network of yeasts and filamentous cells deeply embedded in exopolymeric matrix. These biofilms were intrinsically… CONTINUE READING

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Characteristics of biofilm formation by Candida albicans

  • G. Ramage, K. Vande Walle, B. L. Wickes, J. L. Lopez-Ribot
  • Revista Iberoamericana de Micología
  • 2001

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