Investigation of mRNA expression of tumor necrosis factor-alpha, interleukin-1beta, and cyclooxygenase-2 in cultured equine digital artery smooth muscle cells after exposure to endotoxin.

@article{Rodgerson2001InvestigationOM,
  title={Investigation of mRNA expression of tumor necrosis factor-alpha, interleukin-1beta, and cyclooxygenase-2 in cultured equine digital artery smooth muscle cells after exposure to endotoxin.},
  author={Dwayne H. Rodgerson and J Belknap and James N. Moore and Genevieve L Fontaine},
  journal={American journal of veterinary research},
  year={2001},
  volume={62 12},
  pages={1957-63}
}
OBJECTIVE To determine messenger RNA expression of cyclooxygenase (COX)-2, tumor necrosis factor (TNF)-alpha, and interleukin- (IL)-1beta from cultured equine smooth muscle cells (SMC). SAMPLE POPULATION Segments of palmar digital artery harvested from 6 clinically normal adult horses. PROCEDURE Explants were collected from the tunica media of arteries for primary culture of SMC. Equine mononuclear cells were used as control cells. Subcultured vascular SMC and control cells were exposed to… CONTINUE READING
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