Investigation of living pancreas tumor cells by digital holographic microscopy.

  title={Investigation of living pancreas tumor cells by digital holographic microscopy.},
  author={Bj{\"o}rn Kemper and Daniel Carl and Juergen Schnekenburger and Ilona Bredebusch and Marcus Sch{\"a}fer and Wolfram Domschke and Gert von Bally},
  journal={Journal of biomedical optics},
  volume={11 3},
Digital holographic microscopy provides new facilities for contactless and marker-free quantitative phase contrast imaging. In this work, a digital holographic microscopy method for the integral refractive index determination of living single cells in cell culture medium is presented. Further, the obtained refractive index information is applied to full field thickness and shape determination of adherent pancreas tumor cells, as well as for analysis of drug-induced dynamic changes of a single… CONTINUE READING