Investigation of injectable drospirenone organogels with regard to their rheology and comparison to non-stabilized oil-based drospirenone suspensions

  title={Investigation of injectable drospirenone organogels with regard to their rheology and comparison to non-stabilized oil-based drospirenone suspensions},
  author={Stefanie Nippe and Sascha General},
  journal={Drug Development and Industrial Pharmacy},
  pages={681 - 691}
  • Stefanie NippeS. General
  • Published 3 April 2015
  • Materials Science, Biology, Engineering
  • Drug Development and Industrial Pharmacy
Abstract The objective of this study was to evaluate organogels as potential injectable drug-delivery systems for drospirenone (DRSP). Recently, studies on organogel characterization with focus on the parenteral injection are rarely to find in the literature. DRSP organogels contained the drug suspended in medium-chain triglycerides and were stabilized by various organogelators. The DRSP organogels were assessed in comparison to non-stabilized DRSP microcrystal suspensions (MCSs). Furthermore… 

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