Investigation of influenza virus polymerase activity in pig cells.

  title={Investigation of influenza virus polymerase activity in pig cells.},
  author={Olivier Moncorg{\'e} and Jason S Long and Anna V Cauldwell and Hongbo Zhou and Samantha Lycett and Wendy S Barclay},
  journal={Journal of virology},
  volume={87 1},
Reassortant influenza viruses with combinations of avian, human, and/or swine genomic segments have been detected frequently in pigs. As a consequence, pigs have been accused of being a "mixing vessel" for influenza viruses. This implies that pig cells support transcription and replication of avian influenza viruses, in contrast to human cells, in which most avian influenza virus polymerases display limited activity. Although influenza virus polymerase activity has been studied in human and… CONTINUE READING
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