Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities.

@article{Setnika2006InvestigationOG,
  title={Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities.},
  author={Vladim{\'i}r Setni{\vc}ka and Marie Urbanov{\'a} and Karel Volka and Sreenivasachary Nampally and Jean-Marie Lehn},
  journal={Chemistry},
  year={2006},
  volume={12 34},
  pages={
          8735-43
        }
}
The self-assembly of guanosine-5'-hydrazide G-1 in D(2)O, in the presence and absence of sodium cations, has been investigated by chiroptical techniques: electronic (ECD) and the newly introduced vibrational (VCD) circular dichroism spectroscopy. Using a combination of ECD and VCD with other methods such as IR, electron microscopy, and electrospray ionization mass spectrometry (ESI-MS) it was found that G-1 produces long-range chiral aggregates consisting of G-quartets, (G-1)(4), subsequently… Expand
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TLDR
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