Investigation of germinative cells in generating and renewed anagen hair apparatus in mice using anti-bromodeoxyuridine monoclonal antibody.

@article{Tezuka1991InvestigationOG,
  title={Investigation of germinative cells in generating and renewed anagen hair apparatus in mice using anti-bromodeoxyuridine monoclonal antibody.},
  author={Masakatsu Tezuka and Mayumi Ito and Kei Ito and Toshio Tazawa and Yasufumi Sato},
  journal={Journal of dermatological science},
  year={1991},
  volume={2 6},
  pages={434-43}
}
To elucidate the cell kinetics in generating and renewed anagen hair apparatus in mice, S-phase cells in dorsal skin of new-born and 14 to 25-day-old mice were labeled with bromodeoxyuridine (BrdU) and stained immunohistochemically using anti-BrdU monoclonal antibody. In primary hair germ, lower and outer cells were positively stained. In hair peg, the positive cells were divided into upper and lower portions. In bulbous hair peg, the lower positive cells gathered at the suprapapillary area… CONTINUE READING