Investigation of general and cytoskeletal markers to estimate numbers and proportions of neurons in the human intestine.

@article{Ganns2006InvestigationOG,
  title={Investigation of general and cytoskeletal markers to estimate numbers and proportions of neurons in the human intestine.},
  author={D Ganns and Falk Schroedl and Winfried L Neuhuber and Axel Brehmer},
  journal={Histology and histopathology},
  year={2006},
  volume={21 1},
  pages={41-51}
}
An important requirement in pathological diagnostics in the human enteric nervous system (ENS) is the estimation of the total numbers of neurons and of proportions of distinct subpopulations. In this study, we compared the suitability of two suggested panneuronal markers, cuprolinic blue (CB) and anti-Hu-protein (HU), for staining and counting human myenteric neurons in wholemounts, derived from small and large intestinal samples. Furthermore, the proportional expression of three cytoskeletal… CONTINUE READING