Investigation of four-dimensional (4D) Monte Carlo dose calculation in real-time tumor tracking stereotatic body radiotherapy for lung cancers.

@article{Chan2012InvestigationOF,
  title={Investigation of four-dimensional (4D) Monte Carlo dose calculation in real-time tumor tracking stereotatic body radiotherapy for lung cancers.},
  author={Mark Chan and Dora L. W. Kwong and Sherry C. Y. Ng and Eric K.W. Tam and Anthony S.M. Tong},
  journal={Medical physics},
  year={2012},
  volume={39 9},
  pages={5479-87}
}
PURPOSE To investigate the dosimetric variations and radiobiological impacts as a consequence of delivering treatment plans of 3D nature in 4D manner based on the 4D Monte Carlo treatment planning framework implemented on Cyberknife. METHODS Dose distributions were optimized on reference 3D images at end of exhale phase of a 4DCT dataset for 25 lung cancer patients treated with 60 Gy∕3Fx or 48 Gy∕4Fx. Deformable image registrations between individual 3DCT images to the reference 3DCT image in… CONTINUE READING

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