Investigation of elemental models in senile dementia and depressives using neutron activation analysis

@article{Akanle1987InvestigationOE,
  title={Investigation of elemental models in senile dementia and depressives using neutron activation analysis},
  author={O. A. Akanle and Nicholas M. Spyrou and A. A. Damyanova and Denis M. Shaw and Layla M. Ali},
  journal={Journal of Radioanalytical and Nuclear Chemistry},
  year={1987},
  volume={113},
  pages={405-416}
}
Instrumental neutron activation analysis has been used to determine the concentration of a range of elements in hair and blood samples, separated into erythrocytes and plasma, obtained from two groups of women, senile demented (9) and depressives (16), and their respective controls (17 and 9). The results suggest that the senile dementia group has significantly higher Al concentrations in erythrocytes and hair relative to the controls but no significant correlation between the aluminium content… 
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References

SHOWING 1-10 OF 19 REFERENCES
Tissue vanadium levels in manic-depressive psychosis.
TLDR
The results suggest that manic patients have significantly raised vanadium levels in hair which fall towards control levels with recovery, but there are no significant differences in the mean vanadium content of whole blood or serum.
Plasma vanadium concentration in manic-depressive illness.
TLDR
The results suggest that vanadium may be a cause of the variations in Na-K-Mg ATPase and sodium pump activity which are associated with manic-depressive illness.
Aluminium, neurofibrillary degeneration and Alzheimer's disease.
TLDR
The aluminium content of 585 areas sampled in 10 post-mortem cases of Alzheimer's disease ranging in age from 50 to 88 years, in which the diagnosis was based on the specific histological appearances, revealed an elevated aluminium content in some regions.
Blood levels of vanadium, caesium, and other elements in depressive patients.
ABNORMALITY OF THE BLOOD-CEREBROSPINAL FLUID BARRIER OF PATIENTS SUFFERING FROM A DEPRESSIVE ILLNESS
  • A. Coppen
  • Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1960
TLDR
There have therefore been many investigations the blood-cerebrospinal fluid barrier in patients suffering and have mostly found mechanisms for ensuring the stability of the internal environment in which neurons function.
Psychogeriatrics and the neo-epidemiologists.
TLDR
It is significant that the WHO report barely mentioned the epidemiological contribution to its subject-matter, and this verdict is difficult to reconcile with the widespread concern aroused by the lengthening human life-span.
Changes in Erythrocyte Sodium and Potassium on Recovery from a Depressive Illness
TLDR
There is evidence that electrolyte changes are closely associated with alteration in cerebral activity, and a significant coefficient of concordance between mean daily urinary sodium potassium ratios, the electroencephalogram mean abundances and word output is reported.
Neurofibrillary changes following childhood lead encephalopathy.
TLDR
The brain revealed diffuse cortical atrophy, most severe in the temporal lobes, followed by hippocampi, amygdaloid nuclei and frontal cortex, and Numerous pyramidal cells of the forebrain grisea contained Alzheimer's neurofibrillary tangles.
...
...