Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol

@article{Sharpe2006InvestigationOD,
  title={Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol},
  author={Rainie L Sharpe and Melissa Drolet and Deborah L Maclatchy},
  journal={Reproductive Biology and Endocrinology},
  year={2006},
  volume={4},
  pages={60 - 60}
}
Total and intra-mitochondrial gonadal cholesterol concentrations are decreased in fish exposed to the phytoestrogen beta-sitosterol (beta-sit). The present study examined the potential for beta-sit to disrupt de novo cholesterol synthesis in the gonads of goldfish exposed to 200 microgram/g beta-sit and 10 microgram/g 17beta-estradiol (E2; estrogenic control) by intra-peritoneal Silastic implants for 21 days. The de novo cholesterol synthetic capacity was estimated by incubating gonadal tissue… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Comparing biological responses to mill process changes: a study of steroid concentrations in goldfish exposed to effluent and waste streams from a canadian bleached sulphite mill

  • JL Parrott, JJ Jardine, +5 authors JH Carey
  • Wat Sci Tech
  • 1999
Highly Influential
11 Excerpts

Cholesterol biosynthesis, storage, and mobilization in steroidogenic organs

  • RC Pederson
  • In Biology of Cholesterol Edited by: Yeagle PL…
  • 1988
Highly Influential
5 Excerpts

MacLatchy DLM: Lipid dynamics in goldfish (Carassius auratus) during a period of gonadal recrudescence: effects of b-sitosterol and 17b-estradiol exposure

  • RL Sharpe
  • Comp Biochem Physiol
  • 2006
1 Excerpt

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