Investigation of clinical pharmacokinetic variability of an opioid antagonist through physiologically based absorption modeling.


Identifying the source of inter- and/or intrasubject variability in pharmacokinetics (PK) provides fundamental information in understanding the pharmacokinetics-pharmacodynamics relationship of a drug and project its efficacy and safety in clinical populations. This identification process can be challenging given that a large number of potential causes… (More)
DOI: 10.1002/jps.23629


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.