Investigation of chloramphenicol acetyltransferase formation byEscherichia coli K-12 cells after changes in intracellular cyclic AMP concentration


The effect of cylic AMP, ACTH, and glucose on formation of the enzyme chloramphenicol acetyltransferase by cells ofEscherichia coli CSH-2/R222 andE. coli WZ-78/R222 (cya855) was investigated. Glucose was shown to reduce synthesis of the enzyme inE. coli CSH-2/R222 by inducing catabolite repression; this could be overcome by 5 mM cyclic AMP and 1000 μg/ml… (More)
DOI: 10.1007/BF00804912


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