Investigation of c-KIT and Ki67 expression in normal, preneoplastic and neoplastic canine prostate

@inproceedings{FonsecaAlves2017InvestigationOC,
  title={Investigation of c-KIT and Ki67 expression in normal, preneoplastic and neoplastic canine prostate},
  author={Carlos Eduardo Fonseca-Alves and Priscilla Emiko Kobayashi and Chiara Palmieri and Ren{\'e}e Laufer-Amorim},
  booktitle={BMC veterinary research},
  year={2017}
}
BACKGROUND c-KIT expression has been related to bone metastasis in human prostate cancer, but whether c-KIT expression can be similarly classified in canine prostatic tissue is unknown. This study assessed c-KIT and Ki67 expression in canine prostate cancer (PC). c-KIT gene and protein expression and Ki67 expression were evaluated in forty-four canine prostatic tissues by immunohistochemistry, RT-qPCR and western blot. Additionally, we have investigated c-KIT protein expression by… CONTINUE READING