Investigation of MMP-2 and -9 in a highly invasive A431 tumor cell sub-line selected from a Boyden chamber assay.

@article{Kao2008InvestigationOM,
  title={Investigation of MMP-2 and -9 in a highly invasive A431 tumor cell sub-line selected from a Boyden chamber assay.},
  author={Wen-Te Kao and Chun-Yu Lin and Lung-Ta Lee and Ping-Ping Hwang Lee and Chin-Chun Hung and Yung-Sheng Lin and Shih-Hsun Chen and Ferng-Chun Ke and Jiuan-Jiuan Hwang and Ming-Ting Lee},
  journal={Anticancer research},
  year={2008},
  volume={28 4B},
  pages={
          2109-20
        }
}
In this study, highly invasive tumor cell lines (designated A431-I, -II and -III) derived from parental A431 tumor cells (A431-P) were isolated by three successive passages through a Boyden chamber with matrigel-coated membrane support. The invasive potential and the activity of secreted MMP-9 of each sub-line increased significantly compared to the A431-P (A431-III > A431-II > A431-I) as evidenced by the in vitro invasion assay, gelatin zymography and immunoblotting analyses. RT-PCR results… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

  • International journal of oncology
  • 2019
VIEW 3 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Neurotrophic artemin promotes motility and invasiveness of MIA PaCa-2 pancreatic cancer cells.

  • Asian Pacific journal of cancer prevention : APJCP
  • 2012
VIEW 1 EXCERPT
CITES METHODS

Similar Papers

Loading similar papers…