Investigation of BAX and BCL2 expression and apoptosis in a resveratrol- and prednisolone-treated human T-ALL cell line, CCRF-CEM

@article{Khanzadeh2018InvestigationOB,
  title={Investigation of BAX and BCL2 expression and apoptosis in a resveratrol- and prednisolone-treated human T-ALL cell line, CCRF-CEM},
  author={Taghi Khanzadeh and Majid Farshdousti Hagh and Mehdi Talebi and Bahman Yousefi and Ako Azimi and Abbas Ali Hossein pour feizi and Behzad Baradaran},
  journal={Blood research},
  year={2018},
  volume={53},
  pages={53 - 60}
}
Background The numerous side effects and chemo-resistance of conventional chemical drugs in the treatment of malignancies have led to consideration of the anti-cancer properties of natural products. In the present study, we aimed to explore the apoptotic effect of two natural components, resveratrol and prednisolone, on the T acute lymphoblastic leukemia (ALL) cell line, CCRF-CEM. Our findings suggested the incorporation of these natural agents into drug regimens to treat patients with ALL… 

Figures from this paper

Apoptotic effect of resveratrol on human T‐ALL cell line CCRF‐CEM is unlikely exerted through alteration of BAX and BCL2 promoter methylation
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