Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice.

@article{Verma2016InvestigatingTR,
  title={Investigating the role of nisoldipine in foot-shock-induced post-traumatic stress disorder in mice.},
  author={Meenu Verma and Anjana Bali and Nirmal Singh and Amteshwar Singh Jaggi},
  journal={Fundamental & clinical pharmacology},
  year={2016},
  volume={30 2},
  pages={128-36}
}
This study was designed to investigate the effectiveness of nisoldipine, an L-type voltage-sensitive calcium channel blocker, to ameliorate anxiety and fear response in a mouse model of post-traumatic stress disorder (PTSD). Acute trauma was induced in Swiss albino mice in a 2-day electric foot-shock paradigm consisting of 15 intermittent foot-shocks of 0.8… CONTINUE READING