Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication.

@article{Singaravelu2014InvestigatingTA,
  title={Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication.},
  author={Ragunath Singaravelu and Julie Delcorde and Rodney K. Lyn and Rineke Steenbergen and D. J. Mazzocchi Jones and D. Lorne Tyrrell and Rodney S Russell and John Paul Pezacki},
  journal={The FEBS journal},
  year={2014},
  volume={281 16},
  pages={3751-65}
}
Cell-death-inducing DFF45-like effector B (CIDEB) is an apoptotic host factor, which was recently found to also regulate hepatic lipid homeostasis. Herein we delineate the relevance of these dual roles of CIDEB in apoptosis and lipid metabolism in the context of hepatitis C virus (HCV) replication. We demonstrate that HCV upregulates CIDEB expression in… CONTINUE READING