Investigating neuroblastoma in childhood opsoclonus-myoclonus syndrome.

@article{Brunklaus2012InvestigatingNI,
  title={Investigating neuroblastoma in childhood opsoclonus-myoclonus syndrome.},
  author={Andreas Brunklaus and Kristina Pohl and Sameer M Zuberi and Carlos de Sousa},
  journal={Archives of disease in childhood},
  year={2012},
  volume={97 5},
  pages={
          461-3
        }
}
OBJECTIVE Opsoclonus-myoclonus syndrome (OMS) is a serious, often disabling neurological illness of early childhood which is frequently associated with occult neuroblastoma. As investigation methods vary significantly, the authors assessed the usefulness of imaging and metabolic studies in tumour detection. METHODS Retrospective case note review of 101 OMS patients from two paediatric neurology centres over 53 years. RESULTS The prevalence of neuroblastoma in OMS was 8% in the 1970s, 16% in… CONTINUE READING

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