Investigating incoherence gives insight: clopidogrel is equivalent to extended-release dipyridamole plus aspirin in secondary stroke prevention.

@article{Dewilde2012InvestigatingIG,
  title={Investigating incoherence gives insight: clopidogrel is equivalent to extended-release dipyridamole plus aspirin in secondary stroke prevention.},
  author={Sarah Dewilde and Neil M. Hawkins},
  journal={Journal of clinical epidemiology},
  year={2012},
  volume={65 8},
  pages={835-45}
}
OBJECTIVE To identify confounding factors that may explain the incoherence between direct and indirect evidence in a published analysis comparing extended-release dipyridamole (ERDP) plus aspirin to clopidogrel for the reduction of stroke. STUDY DESIGN AND SETTING An existing analysis was updated with new studies from a systematic literature review. Clinicians reviewed the studies for potential confounders. Network meta-analyses were conducted including or excluding potential confounders, and… CONTINUE READING

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Assessing evidence inconsistency in mixed treatment comparisons

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