Investigating gene-to-behavior pathways in psychiatric disorders: the use of a comprehensive behavioral test battery on genetically engineered mice.

@article{Takao2006InvestigatingGP,
  title={Investigating gene-to-behavior pathways in psychiatric disorders: the use of a comprehensive behavioral test battery on genetically engineered mice.},
  author={Keizo Takao and Tsuyoshi Miyakawa},
  journal={Annals of the New York Academy of Sciences},
  year={2006},
  volume={1086},
  pages={
          144-59
        }
}
We have been investigating the relationships between genes and behaviors by conducting a systematic and well-defined behavioral test battery with mice that have a mutation on a gene of interest. The behavioral test battery covers a relatively broad range of various behavioral domains such as learning and memory, sensory-motor functions, emotion, motivation, and drug sensitivity/preference. Recently, we subjected mice lacking calcineurin (CN), a calcium/calmodulin protein phosphatase, to the… CONTINUE READING

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