Investigating correlations in the altered metabolic profiles of obese and diabetic subjects in a South Indian Asian population using an NMR-based metabolomic approach.

@article{Gogna2015InvestigatingCI,
  title={Investigating correlations in the altered metabolic profiles of obese and diabetic subjects in a South Indian Asian population using an NMR-based metabolomic approach.},
  author={Navdeep Gogna and M S R Krishna and Anup Mammen Oommen and Kavita Dorai},
  journal={Molecular bioSystems},
  year={2015},
  volume={11 2},
  pages={595-606}
}
It is well known that obesity/high body mass index (BMI) plays a key role in the evolution of insulin resistance and type-2 diabetes mellitus (T2DM). However, the exact mechanism underlying its contribution is still not fully understood. This work focuses on an NMR-based metabolomic investigation of the serum profiles of diabetic, obese South Indian Asian subjects. (1)H 1D and 2D NMR experiments were performed to profile the altered metabolic patterns of obese diabetic subjects and multivariate… CONTINUE READING
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